Zolvix
Zolvix
Product Description
Zolvix is a highly effective, broad-spectrum anthelmintic designed to control a wide range of gastrointestinal nematode infections in sheep. It is specifically formulated to treat lambs, hoggets, breeding rams, and ewes, including pregnant and lactating ewes. This product is particularly valuable in cases where parasites have developed resistance to other common classes of anthelmintics, such as white drenches (pro-benzimidazoles), yellow drenches (levamisole), clear drenches (macrocyclic lactones), and morantel.
Zolvix contains the active ingredient monepantel, a member of the amino-acetonitrile derivative (AAD) class of anthelmintics. It has been shown to be effective against a wide spectrum of parasites, including those that are resistant to other classes of dewormers, providing a powerful solution for managing parasitic resistance in sheep farming.
Parasites Covered (Spectrum of Activity)
Zolvix offers robust protection against a wide variety of gastrointestinal nematodes, including both fourth-stage larvae and adult forms of many key parasite species. These include:
- Haemonchus contortus (Barber’s pole worm) – including inhibited larvae, which are particularly difficult to treat with other anthelmintics.
- Teladorsagia circumcincta (Brown stomach worm) – including inhibited larvae.
- Teladorsagia trifurcata – including inhibited larvae.
- Teladorsagia davtiani – including inhibited larvae.
- Trichostrongylus axei – a common stomach worm.
- Trichostrongylus colubriformis – a small intestinal worm.
- Trichostrongylus vitrinus – another species of intestinal worm.
- Cooperia curticei – a common intestinal worm in young sheep.
- Cooperia oncophora – another intestinal worm species affecting sheep.
- Nematodirus battus – an important cause of disease in lambs, known for its distinctive large eggs.
- Nematodirus filicollis – a similar species to Nematodirus battus.
- Nematodirus spathiger – another species of Nematodirus.
- Chabertia ovina – commonly known as the large-mouthed bowel worm.
- Oesophagostomum venulosum – also known as the nodular worm.
Mode of Action
Zolvix’s active ingredient, monepantel, works by targeting the nicotinic acetylcholine receptors in the nervous system of nematodes, which are essential for their survival. Monepantel’s unique mode of action disrupts nerve signals in the parasite, causing paralysis and death. This mechanism is distinct from other anthelmintic classes, making it a key tool for combating nematode populations that have developed resistance to other treatments.
Dosage and Administration
The recommended dose for Zolvix is 2.5 mg of monepantel per kilogram of the animal’s bodyweight. It is essential to accurately determine the bodyweight of each animal or group of animals to ensure the correct dose is administered. Under-dosing can reduce the effectiveness of the treatment and contribute to the development of resistance, while overdosing can lead to wastage of the product and increase the risk of adverse reactions.
- Administration: The product should be administered as a single oral dose using appropriate drenching equipment. For best results, administer the dose to the back of the sheep’s tongue to ensure the animal swallows it completely.
- If treating animals in groups, it is recommended to group them by similar bodyweight and dose according to the heaviest animal in each group to avoid underdosing the larger individuals.
- Ensure that drenching equipment is properly calibrated and functioning to deliver the correct dosage. After use, the equipment should be thoroughly cleaned to maintain hygiene and prevent cross-contamination.
- Repeat Treatment: Depending on the epidemiological situation in the region, it may be necessary to repeat the treatment. This can vary based on the parasite burden in the area and the management practices on the farm.
Withdrawal Period
To ensure food safety, Zolvix has a strict withdrawal period for sheep intended for meat production. After treatment, there must be a 7-day withdrawal period before the animal can be slaughtered for human consumption. This ensures that any residues of the active ingredient, monepantel, are cleared from the animal’s system, maintaining food safety standards.
Key Benefits
- Broad-Spectrum Control: Effective against a wide range of gastrointestinal nematodes, including resistant strains.
- Unique Mode of Action: Targets parasites resistant to other anthelmintic classes, making it an ideal solution for managing parasitic resistance.
- Safe for Use in Pregnant and Lactating Ewes: Zolvix can be safely administered during all stages of pregnancy and lactation, offering flexibility for farmers managing breeding stock.
- Short Withdrawal Period: The 7-day withdrawal period ensures minimal disruption to meat production schedules while adhering to food safety regulations.
Packaging
Zolvix is available in a 2.5-litre container, suitable for larger flocks or farms requiring repeated treatment. The packaging is designed for ease of use with standard drenching equipment, and the container provides sufficient volume for multiple treatments, depending on flock size and the animals’ body weight.
In conclusion, Zolvix is a highly effective and reliable option for sheep farmers dealing with gastrointestinal nematode infections, especially in areas where resistance to other anthelmintics is an issue. Its broad-spectrum activity, safety profile, and short withdrawal period make it a versatile tool in the ongoing management of parasite burdens in sheep.
You can download the datasheet here
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